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Updated: 2017 Aug. 1

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Warning – Occasionally the phosphosites shown below in more divergent species may be slightly mis-aligned with our algorithm and the calculated Conservation Score may be higher than shown.
Phosphosite   Conservation Score
Human Protein: EPHB3 All Species: 20.3
Human Site: T448 Identified Species: 55.83
UniProt: P54753 Number Species: 8
    Phosphosite Substitution
    Charge Score: 0
Phosphosite
Sequences
Species Species
Scientific Name
UniProt ID NCBI Ref Seq ID AA# Mr(Da) P-Site -7 -6 -5 -4 -3 -2 -1 0 1 2 3 4 5 6 7
Human Homo sapiens P54753 NP_004434.2 998 110330 T448 Y A A V N I T T N Q A A P S E
Chimpanzee Pan troglodytes P0C0K6 1020 110674 T482 A A A I N V S T S H E V P S A
Rhesus Macaque Macaca mulatta XP_001097522 1001 110812 T451 Y A A V N I T T N Q A A P S E
Dog Lupus familis XP_545232 1132 124546 T582 Y A A V N I T T N Q A A P S E
Cat Felis silvestris
Mouse Mus musculus P54754 993 109567 T443 Y A A V N I T T N Q A A P S E
Rat Rattus norvegicus P09759 984 109865 Q431 S V N I T T N Q A A P S T V P
Wallaby Macropus eugenll
Platypus Ornith. anatinus
Chicken Gallus gallus Q07498 988 109560 S437 P T M H L H S S T G N S M T L
Frog Xenopus laevis Q91735 974 108246 M433 A A P S S V P M V Q S H G S L
Zebra Danio Brachydanio rerio O13146 981 109636 T438 L V S V N V T T S Q T V S V I
Tiger Blowfish Takifugu rubipres
Fruit Fly Dros. melanogaster
Honey Bee Apis mellifera
Nematode Worm Caenorhab. elegans
Sea Urchin Strong. purpuratus
Poplar Tree Populus trichocarpa
Maize Zea mays
Rice Oryza sativa
Thale Cress Arabidopsis thaliana
Baker's Yeast Sacchar. cerevisiae
Red Bread Mold Neurospora crassa
Conservation
Percent
Protein Identity: 100 47.3 97.6 85.6 N.A. 95.9 70.2 N.A. N.A. 83.3 77.4 54.7 N.A. N.A. N.A. N.A. N.A.
Protein Similarity: 100 63.5 98.3 86.2 N.A. 96.7 81.6 N.A. N.A. 90.6 87.5 69 N.A. N.A. N.A. N.A. N.A.
P-Site Identity: 100 40 100 100 N.A. 100 0 N.A. N.A. 0 20 33.3 N.A. N.A. N.A. N.A. N.A.
P-Site Similarity: 100 66.6 100 100 N.A. 100 13.3 N.A. N.A. 26.6 40 53.3 N.A. N.A. N.A. N.A. N.A.
Percent
Protein Identity: N.A. N.A. N.A. N.A. N.A. N.A.
Protein Similarity: N.A. N.A. N.A. N.A. N.A. N.A.
P-Site Identity: N.A. N.A. N.A. N.A. N.A. N.A.
P-Site Similarity: N.A. N.A. N.A. N.A. N.A. N.A.
Phosphosite
Consensus
Position -7 -6 -5 -4 -3 -4 -5 0 +1 +2 +3 +4 +5 +6 +7
% Ala: 23 67 56 0 0 0 0 0 12 12 45 45 0 0 12 % A
% Cys: 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 % C
% Asp: 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 % D
% Glu: 0 0 0 0 0 0 0 0 0 0 12 0 0 0 45 % E
% Phe: 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 % F
% Gly: 0 0 0 0 0 0 0 0 0 12 0 0 12 0 0 % G
% His: 0 0 0 12 0 12 0 0 0 12 0 12 0 0 0 % H
% Ile: 0 0 0 23 0 45 0 0 0 0 0 0 0 0 12 % I
% Lys: 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 % K
% Leu: 12 0 0 0 12 0 0 0 0 0 0 0 0 0 23 % L
% Met: 0 0 12 0 0 0 0 12 0 0 0 0 12 0 0 % M
% Asn: 0 0 12 0 67 0 12 0 45 0 12 0 0 0 0 % N
% Pro: 12 0 12 0 0 0 12 0 0 0 12 0 56 0 12 % P
% Gln: 0 0 0 0 0 0 0 12 0 67 0 0 0 0 0 % Q
% Arg: 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 % R
% Ser: 12 0 12 12 12 0 23 12 23 0 12 23 12 67 0 % S
% Thr: 0 12 0 0 12 12 56 67 12 0 12 0 12 12 0 % T
% Val: 0 23 0 56 0 34 0 0 12 0 0 23 0 23 0 % V
% Trp: 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 % W
% Tyr: 45 0 0 0 0 0 0 0 0 0 0 0 0 0 0 % Y
% Spaces: 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 % _